Research finds drug-resistant Campylobacter jejuni connection to pet retailer puppies

In response to a examine, strains of drug-resistant Campylobacter jejuni have been circulating since a minimum of 2011 and are related to sickness amongst pet retailer clients, staff, and others who come into contact with pet retailer puppies.

The examine was revealed in JAMA Community Open and led by Louise Okay. Francois Watkins, MD, MPH,  a researcher with the Facilities of Illness Management and Prevention.

In response to the CDC, Campylobacter causes an estimated 1.5 million diseases in individuals every year in the USA.

Individuals can get Campylobacter infections by consuming uncooked or undercooked poultry or consuming one thing that touched it. They’ll additionally get it from consuming different meals, together with seafood, meat, and produce, by contact with animals and by consuming untreated water.

Extensively drug-resistant Campylobacter jejuni infections can’t be handled with any generally really useful antibiotics and pose an rising public well being menace, in line with the report. 

This survey examine recognized 168 instances from public well being stories of Campylobacter infections with an epidemiologic or molecular hyperlink to pet retailer puppies from 2011 to 2020. 

A complete of 97 % of sufferers reported contact with a canine, and 88 % of these reported contact with a pet retailer pet. Isolates had been proof against seven antibiotic courses, together with all really useful therapy brokers.

Historical past of instances
In Aug. 2017, well being officers recognized sufferers with Campylobacter jejuni infections who reported contact with puppies bought by pet shops.

The CDC investigated instances of culture-confirmed Campylobacter jejuni infections in U..S. sufferers with an epidemiologic or molecular affiliation with pet retailer puppies between Jan. 1, 2016, and Feb. 29, 2020. 

Accessible data from instances occurring earlier than 2016 with genetically associated isolates had been additionally obtained. 

Survey interviews
Sufferers had been interviewed about demographic traits, well being outcomes and canine publicity throughout the seven days earlier than sickness onset.

Laboratories used core genome multilocus sequence typing to evaluate isolate relatedness, and genomes had been screened for resistance determinants to foretell antibiotic resistance. Isolates proof against fluoroquinolones, macrolides and three or extra extra antibiotic courses had been thought-about to be extensively drug resistant. Circumstances earlier than 2016 had been recognized by screening all sequenced isolates submitted for surveillance utilizing core genome multilocus sequence typing. 


  • A complete of 168 sufferers (median [interquartile range] age, 37 [19.5-51.0] years
  • 105 of 163 sufferers had been feminine, 64 %, with an epidemiologic or molecular affiliation with pet retailer puppies studied
  • A complete of 137 instances occurred from Jan. 1, 2016, to Feb. 29, 2020, with 31 extra instances courting again to 2011
  • Total, 117 of 121 sufferers, 97 %, reported contact with a canine within the week earlier than symptom onset, of whom 69 of 78, for 88 %, with extra data obtainable reported contact with a pet retailer pet
  • 168 isolates, 88 %, had been extensively drug resistant
  • Traceback investigation didn’t implicate any specific breeder, transporter, distributor, retailer or chain

The outcomes of this examine recommend that well being care suppliers ought to ask about pet publicity when treating sufferers with Campylobacter an infection, particularly when they don’t enhance with routine antibiotics.

The examine additionally means that the business canine trade ought to take motion to assist forestall the unfold of extensively drug-resistant Campylobacter jejuni from pet retailer puppies to individuals.

The complete examine could be considered right here.

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